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Skin care Netherlands NL Outessa Keywords:skin-careskin treatmentsdermatologyJessica WuPatricia WexlerNorman LeafMelanie SimonMichael GalitzerFredric BrandtDavid ColbertNi'Kita WilsonAva ShambanRestylaneJuvedermDebra JalimanRadiesseKaryn GrossmanJeannette GrafZytazeRand RusherShani DardenThermageCoolSculpting Compounding toolkit Rid bacteria and soothe acne-prone skin. Look for: marula oil. Get Email Offers Sign up for great offers from Costco.com! Neo Nude On Sale Our Team Recipes Crema Nera Supreme Reviving Cream Review All The Littles™ JAAD quizzes 5.0 out of 5 starsNice A study was published on the action of topical 0.3% estriol and 0.01% 17β-estradiol in 59 patients (Schmidt et al 1996). The criteria evaluated by the authors were profilometry, corneometry, and clinical signs. Wrinkle depth was significantly reduced and skin hydration was improved. Apart from a rise in prolactin, no other systemic hormonal effects were detected. 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