Health Professionals The causes of neurodermatitis are many and varied. Genetic predisposition, environmental factors as well as inflammation taking place in the skin play a role. This reduced skin barrier is caused by a deficiency, an imbalance or defective functioning of substances (e.g. proteins or fats) that are responsible for the formation of the upper layer of the skin. As a result, more water evaporates and the skin becomes dry. In addition, the skin becomes more permeable to allergens and other environmental substances. These can trigger inflammatory reactions.  Ferri FF. Lichen simplex chronicus. In: Ferri's Clinical Advisor 2016. Philadelphia, Pa.: Mosby Elsevier; 2016. https://www.clinicalkey.com. Accessed July 29, 2015. Sowden JM CON-20375618 Slideshow Things That Can Hurt Your Joints Connect with Wiley Disease Reference Siegfried E All About Pregnancy Hair and scalp problems Stress and Health Research Chief Editor Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin. Accessing Your Medical Records Living With AFib See, Play and Learn Already a print subscriber? Claim online access Histogenesis 1 Supplements and Vitamins Educators at Mayo Clinic train tomorrow’s leaders to deliver compassionate, high-value, safe patient care. Choose a degree.. Inflammation Wolff K, et al. Eczema/Dermatitis. In: Fitzpatrick's Color Atlas and Synopsis of Clinical Dermatology. 7th ed. New York, N.Y.: The McGraw-Hill Companies; 2013. http://www.accessmedicine.com. Accessed Aug. 5, 2015. 3-D animated image library Novak N Thestrup-Pedersen K Chronic urticaria—for public I have read and accept the Wiley Online Library Terms and Conditions of Use. Audio Clinical Practice See all (111) World Allergy Organization - IAACI Prurigo nodularis is characterized by the rash of papules of a hemispherical shape, not prone to fusion and grouping and accompanying by severe itching. Find a Dermatologist (American Academy of Dermatology) Ways to Donate Apps for smartphones: e-symptoms, PasseportAllergie (in German, French, Italian and English) AAFA's Positions and Statements Email to a friend Allergen of the Month Share on Facebook Williams H, Flohr C. How epidemiology has challenged 3 prevailing concepts about atopic dermatitis. J Allergy Clin Immunol. 2006 Jul. 118(1):209-13. [Medline]. Back HELP & SUPPORT Contact Us For ingredients and more, select a product. Symptoms you've been having and for how long Are there other possible causes? Other articles on the topic Amazon Currency Converter Slideshows Four Medicines Approved for NHS Scotland Adamek C Massachusetts Smith FJ, Irvine AD, Terron-Kwiatkowski A, et al. Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris. Nat Genet. 2006 Mar. 38(3):337-42. [Medline]. When it comes to traveling in a car with your dog, safety should be paramount for you both. However, a recent study from Volvo Car USA found some surprising statistics. SOA Product Directory Pet Care Essentials Stage of disease severity Frequency Multimedia Free resources Find an Eczema Expert Please note: By clicking on this link, you will be leaving this Sanofi US and Regeneron website and going to another, entirely independent, website. Sanofi US and Regeneron provide these links as a service to their website visitors and users; however, they take no responsibility for the information on any website but their own. Runny nose MANAGING AD Topical steroids (current mainstay of treatment; commonly used in conjunction with moisturizers): Hydrocortisone, triamcinolone, or betamethasone; ointment bases are generally preferred, particularly in dry environments For elimination and circulation of dampness – LI 4, St 25, TW 6 and Sp 9, St 40, Lu 5. atopic dermatitis | protopic atopic dermatitis | eczema on hands atopic dermatitis | itch
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