Seborrheic dermatitis is a superficial fungal disease of the skin, occurring in areas rich in sebaceous glands. It is thought that an association exists between Malassezia yeasts and seborrheic dermatitis. This may, in part, be due to an abnormal or inflammatory immune response to these yeasts. The azoles represent the largest class of antifungals used in the treatment of this disease to date. In addition to their antifungal properties, some azoles, including bifonazole, itraconazole, and ketoconazole, have demonstrated anti-inflammatory activity, which may be beneficial in alleviating symptoms. Other topical antifungal agents, such as the allylamines (terbinafine), benzylamines (butenafine), hydroxypyridones (ciclopirox), and immunomodulators (pimecrolimus and tacrolimus), have also been effective. In addition, recent studies have revealed that tea tree oil (Melaleuca oil), honey, and cinnamic acid have antifungal activity against Malassezia species, which may be of benefit in the treatment of seborrheic dermatitis. In cases where seborrheic dermatitis is widespread, the use of an oral therapy, such as ketoconazole, itraconazole, and terbinafine, may be preferred. Essentially, antifungal therapy reduces the number of yeasts on the skin, leading to an improvement in seborrheic dermatitis. With a wide availability of preparations, including creams, shampoos, and oral formulations, antifungal agents are safe and effective in the treatment of seborrheic dermatitis. More in AFP Impetigo Excellence in Dermatology™ LOG IN | REGISTER Eczema and Your Health Care All Taxonomy Resources... Hypopigmentation, pruritus, skin atrophy, stinging Health A-Z GARY W. CLARK, MD, MPH, Madigan Army Medical Center, Tacoma, Washington Infectious Disease Advisor > Decision Support in Medicine > Infectious Diseases > Seborrheic dermatitis American Academy of Dermatology: "Seborrheic dermatitis." Population Health and Wellness Programs Table 1. PubMed Central Malassezia species RESOURCES Living Healthy 4. Selden, S. (2010). “Seborrheic Dermatitis: Follow-up.” eMedicine from WebMD. : http://emedicine.medscape.com/article/1108312-overview Facebook Twitter Instagram Click here to login   |  Click here to register Cradle cap appears as patchy scaling or thick crusts on the scalp and greasy skin covered with flaky white or yellow scales. Cradle cap usually doesn't bother the infant. Itching for a Cure Walk Additional Contributors The Association With Cardiovascular Disease and Type 2 Diabetes in Adults With Atopic Dermatitis Search Table 2. Seborrheic dermatitis can often look like – or even appear with – other skin conditions such as atopic dermatitis and psoriasis. SHARE Red skin Philanthropy in Action What are the clinical features of seborrhoeic dermatitis? APA Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Sometimes, seborrheic dermatitis will clear up by itself. More often, it's a lifelong issue that clears and flares. It can last for years at a time, but you can usually control it with good skin care. Why see a board-certified dermatologist? In skin folds under arms and on legs Seborrhoeic Dermatitis – British Association of Dermatologists Meetings Calendar Low- or mid-potency topical corticosteroids have been successful in reducing symptoms of seborrheic dermatitis and are as effective as antifungal and other anti-inflammatory agents.22,29 Although they are effective and cost significantly less than topical antifungals and calcineurin inhibitors, topical corticosteroids are best used as second-line agents because long-term use has been associated with thinning of the skin and formation of telangiectasia.2,18,19,22,26,28,29,32 Yellow, greasy scale on the scalp. With your help, we can update and expand the website. Philanthropy at Mayo Clinic Control Allergies Rarely, the patient will have erythroderma. Our Products Belew PW, Rosenberg EW, Jennings BR. Activation of the alternative pathway of complement by Malassezia ovalis (Pityrosporum ovale). Mycopathologia. 1980 Mar 31. 70(3):187-91. [Medline]. MLA All references are available in the References tab. Typical features include:  There are a variety of treatments of Seborrheic dermatitis. Eradicating the Malasezia yeast appears to be important in the treatment. For this reason, I generally recommend use of various anti-dandruff shampoos including those containing zinc pyrithione, selenium sulphide, ketoconazole, and ciclopirox. These should be left on the scalp for 1-5 minutes depending on the specific patient's scalp. Anti-dandruff shampoos can be drying, and so careful monitoring is needed to determine how best to use these for any given patent.  Poison Ivy The mainstay of therapy remains topical antifungals with creams, gels, foams, liquids, and shampoos. What are the clinical features of seborrhoeic dermatitis? Seborrheic dermatitis occurs in persons of all races. Students Acute Skin Problems On the scalp, many people can get relief by a dandruff shampoos. Camp Discovery Gene Expression Omnibus (GEO) Profiles What is seborrheic dermatitis? Moles/Lesions About the CME program Questions & Answers Rinse well. ARTICLES ON ANDROGENETIC ALOPECIA On the face and body, keep the affected areas clean -- wash with soap and water every day. Sunlight may stop the growth of the yeast organisms that inflame the skin, so being outdoors and outdoor exercise could help make the rash go away. Always be sure to wear sunscreen. Server Error Clothing & Fabrics Treatment of seborrhoeic dermatitis often involves several of the following options. Study notes About AAD Impacted states Population Health and Wellness Programs Dermatitis, Seborrheic/microbiology << Previous article aftershave | rhus dermatitis aftershave | scalp dermatitis aftershave | scalp dermatitis treatment
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