skin condition white spots | vitiligo laser treatment

Sign up for a free Medical News Today account to customize your medical and health news experiences. There are a number of diseases where PUVA is of proven benefit, including psoriasis, mycosis fungoides (cutaneous T-cell lymphoma), and vitiligo. Occasionally, PUVA is also used to treat atopic dermatitis, chronic itching, and certain types of photodermatitis.
Learn about the disorder and treatment choices. This can help you make decisions about your treatment.
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Sometimes the patches continue to widen and spread, but usually they stay in the same place for years. The location of the macules shifts and changes over time, as certain areas of skin lose and regain their pigments. Vitiligo varies in the amount of skin affected. If you have the more generalized form of the disease it may appear with only few spots, or may result in widespread loss of skin color.
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Hann SK Health A-Z Vitiligo is a multifactorial polygenic disorder with a complex pathogenesis. It is related to both genetic and nongenetic factors. Although several theories have been proposed about the pathogenesis of vitiligo, the precise cause remains unknown. Generally agreed upon principles are an absence of functional melanocytes in vitiligo skin and a loss of histochemically recognized melanocytes, owing to their destruction. However, the destruction is most likely a slow process resulting in a progressive decrease of melanocytes. Theories regarding destruction of melanocytes include autoimmune mechanisms, cytotoxic mechanisms, intrinsic melanocyte defects, oxidant-antioxidant mechanisms, and neural mechanisms, as follows:
Initial lesions occur most frequently on the hands, forearms, feet, and face, favoring a perioral and periocular distribution. User guides
Advertise with Us Jump up ^ Chopra, Parul; Niyogi, Rageshree; Katyal, Gauri (2009). Skin and Hair Care: Your Questions Answered. Byword Books Private Limited. p. 2. ISBN 9788181930378. Archived from the original on 23 March 2017.
MORE ABOUT VITILIGO Medical treatments include: Write an article and join a growing community of more than 72,600 academics and researchers from 2,515 institutions.
View all topics Research[edit] Understanding the symptoms of vitiligo Vitiligo is a long-term skin problem that produces white patches of depigmentation on certain sections of skin. Find out about the causes and treatments. Read now
Vitiligo can happen anywhere on the body, but it’s more likely to develop in some areas: Academy resources for:
Van Scott Award and Frost Lectureship FDA, EMA Valsartan Update, New Data on Cancer Risk 178. Rosacea, Acne, Shingles: Common Adult Skin Diseases • Vitiligo Symptoms
Cestari TF Body Hacks Could This Red Bump Be Skin Cancer? What Causes Hives? Vitiligo may also run in families. Children whose parents have the disorder are more likely to develop vitiligo. However, most children will not get vitiligo even if a parent has it.
Nostrils . Segmental vitiligo associated with generalized vitiligo (mixed vitiligo): a retrospective case series of 19 patients. J Am Acad Dermatol. 2011;65(5):965–971pmid:21616559
800.223.2273 Accepted January 27, 2016. Mulekar S Vitiligo typically develops in your twenties, but it can occur at any age. Its cause is currently unknown. Vitiligo may be connected to genetics or autoimmune diseases, such as hyperthyroidism.
The Psychological Impact of Vitiligo Covering up white spots? Dyes work the best. Assessment Get Help for Migraine Relief Today, vitiligo is a treatable condition, though treatment can take two years or longer to regain pigment, and repigmentation may not be 100%. There is more research being conducted than ever before; in Europe, in Asia, and in the U.S., new technologies and research are changing physicians’ approaches to the condition. The recent mapping of the human genome has paved the way for advanced genetic research into vitiligo, and other cell-based theories are also gaining attention.
only $62.00 per issue Mobile Huizen, J. (2017, November 2). “What are these white spots on my skin?.” Medical News Today. Retrieved from
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Not for children. Cortisol is responsible for the regulation of blood sugar and inflammation, while aldosterone functions by regulating both blood pressure and blood volume by controlling salt and water levels.7
Translations[edit] Naveed Sami, MD, FAAD Assistant Professor, Department of Dermatology, University of Alabama School of Medicine In the end, if people still don’t seem to get it, that’s their problem, not yours. If you’re feeling upset, get support from people you trust, whether that’s a family member, friend, teacher, counselor, or support group. There are plenty of people who love you just the way you are.
Prevention Shakya H Email Alerts Taking a small sample (biopsy) of the affected skin to be examined Pandhi R, 33. Grants from outside organizations Calcineurin Inhibitors Allergy
4. Vitiligo is an acquired depigmenting disorder that affects 0.5% to 2% of the world population. Three different forms are classified according to the distribution of lesions; namely non-segmental, segmental and mixed vitiligo. Vitiligo is associated with polymorphisms in genes involved in the immune response and in melanogenesis. However, environmental factors are required for the development of manifest disease. In general, the diagnosis is clinical and no laboratory tests or biopsies are required. Metabolic alterations are central to current concepts in pathophysiology. They induce an increased generation of reactive oxygen species and susceptibility to mild exogenous stimuli in the epidermis. This produces a senescent phenotype of skin cells, leads to the release of innate immune molecules, which trigger autoimmunity, and ultimately causes dysfunction and death of melanocytes. Clinical management aims to halt depigmentation, and to either repigment or depigment the skin, depending on the extent of disease. New therapeutic approaches include stimulation of melanocyte differentiation and proliferation through α-melanocyte-stimulating hormone analogues and through epidermal stem cell engineering. Several questions remain unsolved, including the connection between melanocyte depletion and stem cell exhaustion, the underlying degenerative mechanisms and the biological mediators of cell death. Overall, vitiligo is an excellent model for studying degenerative and autoimmune processes and for testing novel approaches in regenerative medicine. For an illustrated summary of this Primer, visit:
The main sign of vitiligo is pigment loss that produces milky-white patches (depigmentation) on your skin. Other less common signs may include: Vitiligo is a condition that causes patchy loss of skin coloring (pigmentation). The average age of onset of vitiligo is in the mid-twenties, but it can appear at any age. It tends to progress over time, with larger areas of the skin losing pigment. Some people with vitiligo also have patches of pigment loss affecting the hair on their scalp or body.
180. There is no “cure” for vitiligo. Sometimes patches go away on their own. But when that doesn’t happen, doctors can prescribe treatments that might help even out skin tone. Some of these treatments are things you can try at home; others are done by a doctor.
Thyroid Account administration Member resources The light/white blotches of skin associated with vitiligo form when melanocytes fail to produce melanin. It is not known what causes melanocytes to die or stop producing melanin, but the following may play a role:  
Wang, C. Q. et al. TH17 cells and activated dendritic cells are increased in vitiligo lesions. PLoS ONE 6, e18907 (2011).
Current Issue How to Quit Smoking Modified Protein Improves Vitiligo Symptoms in Mice (National Institute of Arthritis and Musculoskeletal and Skin Diseases)
If these solutions aren’t enough, your doctor may recommend topical corticosteroids. Sapam, R., Agrawal, S., Phil, M. & Dhali, T. K. Systemic PUVA versus narrowband UVB in the treatment of vitiligo: a randomized controlled study. Int. J. Dermatol. 51, 1107–1115 (2012).
Fain PR, Agarwal S, Learn to spot and treat skin conditions commonly found in adults such as acne, eczema, shingles, psoriasis, rosacea, hives, cold sores, razor bumps, athlete’s foot, and more.
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Additional access options: . A randomized comparison of excimer laser versus narrow-band ultraviolet B phototherapy after punch grafting in stable vitiligo patients. J Eur Acad Dermatol Venereol. 2012;26(6):690–695pmid:21711467
. Childhood- and later-onset vitiligo have diverse epidemiologic and clinical characteristics. J Am Acad Dermatol. 2012;66(6):954–958pmid:21982634
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7 Replies to “skin condition white spots | vitiligo laser treatment”

  1. Tinea versicolor[22]
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    It helps to know about treatment options so that you know what is possible. Learning more about vitiligo can help you decide what treatment, if any, feels right for you. You may want to treat, camouflage, or just let the vitiligo be. Only you can decide what’s right for you.
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  2. . Treatment of vitiligo with a topical application of pseudocatalase and calcium in combination with short-term UVB exposure: a case study on 33 patients. Dermatology. 1995;190(3):223–229pmid:7599386
    Alkhateeb, A., Fain, P. R., Thody, A., Bennett, D. C. Spritz, R. A. Epidemiology of vitiligo and associated aut oimmune diseases in Caucasian probands and their families. Pigment Cell Res. 16, 208–214 (2003). This study is a genomic analysis of families with generalized vitiligo, and it revealed mechanisms of genetic susceptibility to autoimmunity.
    Hedstrand, H. et al. The transcription factors SOX9 and SOX10 are vitiligo autoantigens in autoimmune polyendocrine syndrome type I. J. Biol. Chem. 276, 35390–35395 (2001).
    Globally about 1% of people are affected by vitiligo.[3] Some populations have rates as high as 2–3%.[5] Males and females are equally affected.[1] About half show the disorder before age 20 and most develop it before age 40.[1] Vitiligo has been described since ancient history.[1]
    Dell’anna, M. L. & Picardo, M. A review and a new hypothesis for non-immunological pathogenetic mechanisms in vitiligo. Pigment Cell Res. 5, 406–411 (2006).
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  3. The bacteria living in your gut have more to do with your immune system than you might think. Knorre/Shutterstock
    Akter, 34, first noticed a white patch of skin above her eyebrow on her normally brown skin while she was pregnant in her 20s. That patch grew bigger and bigger, and then white patches showed up on her hands and neck.
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    Vitiligo is a condition that causes patchy loss of skin coloring (pigmentation). The average age of onset of vitiligo is in the mid-twenties, but it can appear at any age. It tends to progress over time, with larger areas of the skin losing pigment. Some people with vitiligo also have patches of pigment loss affecting the hair on their scalp or body.
    Note: All information on TeensHealth® is for educational purposes only. For specific medical advice, diagnoses, and treatment, consult your doctor.
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    Symptoms and signs of vitiligo include loss of skin color in the form of depigmented, or white, patches of skin in any location on the body.
    Linthorst Homan MW, Spuls PI, de Korte J et al. “The burden of vitiligo: patient characteristics associated with quality of life.” J Am Acad Dermatol 2009; 61: 411-20
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  5. . Hypnosis in dermatology. Arch Dermatol. 2000;136(3):393–399pmid:10724204
    Typical nonsegmental vitiligo.
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    There is no way to predict how much color a person will lose. Color loss can remain unchanged for years. Some people see patches enlarge and new patches appear. On a rare occasion, the skin may regain its lost color without treatment.
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    After three months, Akter’s face was almost completely free of white patches. About 75 percent of her neck, chest, forearms and shins were re-pigmented with color. Her hands had only minimal freckling.
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