coresatin | leukoderma

In other projects Vitiligo causes white patches on your skin. It can also affect your eyes, mouth, and nose. It occurs when the cells that give your skin its color are destroyed. No one knows what destroys them. It is more common in people with autoimmune diseases, and it might run in families. It usually starts before age 40.
Skin, hair and eye coloring comes from a pigment called melanin. It’s related to an amino acid and is produced by melanocytes, the skin’s pigment-making cells, located in the epidermis (outer layer of skin). People with darker skin tones have more melanin in their skin than people who are fair.
Pictures Twitter Translations[edit] Do not use tanning beds and sun lamps. These are not safe alternatives to the sun. These, too, can burn skin that has lost pigment. Residency Training
IGH is more common in people with light skin and may appear in women at younger ages than it does in men. However, it usually affects women older than 40.
What Is the Prognosis of Vitiligo? What is vitiligo? Image Collection The basic types of repigmentation surgery include the following [6, 7] :
Duration Long term[1] Foot Problems From Bunions to Warts Crime According to Dermatologists  Another method of psoralen treatment, used occasionally for children or patients with small, scattered vitiligo patches, involves the application of a very dilute solution of the drug directly to the affected skin area. This is then exposed to sunlight. Such topical treatment makes a person very susceptible to severe burn and blisters following too much sun exposure. It has the advantages of being done at home, and does not damage the entire skin surface, as PUVA does. Recently, some experts have claimed that another form of light treatment, UVB, is just as effective and safer.
Browse Collections 117. PICMED Grant Print ISSN 0028-4793. Healthy Cats Pernicious anemia is a blood disorder in which the body does not make enough red blood cells due to a lack of vitamin B12 in the blood. Pernicious anemia can develop from a lack of a protein that helps the body absorb vitamin B12, not getting enough B12 in the diet, and certain intestinal conditions that interfere with the absorption of vitamin B12 such as Crohn’s disease, celiac sprue, or ulcerative colitis. There is no cure for pernicious anemia, thus treatment is life-long.
Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology
From Choose a self-tanner that contains dihydroxyacetone. When spending time outdoors, reapply sunscreen: Epidemiology Sharquie, K. E., Noaimi, A. A. & Al-Mudaris, H. A. Melanocytes transplantation in patients with vitiligo using needling micrografting technique. J. Drugs Dermatol. 12, e74–e78 (2013).
Explore Our Departments Describe your type of vitiligo, its location on your body, and the progression of your depigmented patches. Cosmetics. Many different kinds of concealers are available, both over-the-counter and through a dermatologist. Ask your doctor for recommendations and try different brands until you find the one that works best for you.
Facial redness de Moura, M. B., Uppala, R., Zhang, Y., Van Houten, B. & Goetzman, E. S. Overexpression of mitochondrial sirtuins alters glycolysis and mitochondrial function in HEK293 cells. PLoS ONE 9, e106028 (2014).
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Martel, C., Wang, Z. & Brenner, C. VDAC phosphorylation, a lipid sensor influencing the cell fate. Mitochondrion 19, 69–77 (2014). See additional information.
Residents Vitiligo (National Institute of Arthritis and Musculoskeletal and Skin Diseases)
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AAP Journals Catalog Legislative Conference This takes between one and two years, depending on the location of the body being treated. However, in most cases the white spots reappear at the same location, often within just one year after stopping the treatments. This recurrence can be just as devastating as when the white patches first appeared.
Comment deleted violating the aspect of our terms of use This option works best in people with darkly pigmented skin. From
Kostyuk, V. A. et al. Dysfunction of glutathione S-transferase leads to excess 4-hydroxy-2-nonenal and H(2)O(2) and impaired cytokine pattern in cultured keratinocytes and blood of vitiligo patients. Antioxid. Redox Signal. 5, 607–620 (2010).
Skin Discolorations 73. Services Living With HIV AIDS Special Offers . Vitiligo-epidemiological study of 4134 patients at the National Center for Vitiligo and Psoriasis in Central Saudi Arabia. Saudi Med J. 2011;32(12):1291–1296pmid:22159386
Classification[edit] 46. Light treatment Baby Career Center Directions in Residency Mural mural on the wall, who is the fairest city of them all? Chicago is a world-renowned art locale, but if you think our talent is limited to museum walls, think again. We’ve rounded some of the best, brightest and most brilliant murals around town. Locations are included, but due to the nature of the beast, we can’t guarantee all are still in existence.
21st Century Cures Pagovich OE, Wu, J., Zhou, M., Wan, Y. & Xu, A. CD8+ T cells from vitiligo perilesional margins induce autologous melanocyte apoptosis. Mol. Med. Rep. 7, 237–241 (2013).
Whitton ME, Community programs & events Resident Calendar Indoor tanning 77.
A Practical Approach to the Diagnosis and Treatment of Vitiligo in Children
White patches tend to develop in places exposed to the sun and may develop slowly or spread quickly. Vitiligo seems to run in families, and most people first notice skin discoloration in their 20s.
Newborn & Baby World Congress of Dermatology Skin & Your Health Press site
Nicolaidou, E. et al. Childhood- and later-onset vitiligo have diverse epidemiologic and clinical characteristics. J. Am. Acad. Dermatol. 66, 954–958 (2012).
Ginger juice serves as a mild stimulant in increasing blood flow to the white patches.
Academy meeting General information 22. Facial redness See Additional Information. CME Attestation Subscribe
Bedbugs Wu, Y. T., Wu, S. B. & Wie, Y. H. Roles of sirtuins in the regulation of antioxidant defense and bioenergetic function of mitochondria under oxidative stress. Free Radic. Res. 48, 1070–1084 (2014). This study elegantly explores the mitochondria-nucleus network and intra- and extracellular links.
Because vitiligo affects a person’s appearance, it can be upsetting. But it isn’t medically dangerous. It’s not a form of skin cancer. It’s not an infection like MRSA. And it’s definitely not contagious, so you can’t catch it from someone else. In fact, most of the people who have vitiligo are every bit as healthy as everyone else.
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    . Recent advances in childhood vitiligo. Clin Dermatol. 2014;32(4):524–530pmid:25017463
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    Ezzedine K, Diallo A, Leaute-Labreze C, et al. Multivariate analysis of factors associated with early-onset segmental and nonsegmental vitiligo: a prospective observational study of 213 patients. Br J Dermatol. 2011 Jul. 165(1):44-9. [Medline].
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    The American Academy of Dermatology recommends limiting exposure to the sun, using sunscreen every day and wearing sun-protective clothing. Tanning beds should be avoided. So should tattoos. The skin damage a tattoo causes can lead to a new patch of vitiligo. Support groups can be helpful. These include the American Vitiligo Research Foundation, the National Vitiligo Foundation, and VitiligoSupport.com.
    Jump up ^ Lamkanfi M, Vande Walle L, Kanneganti TD (2011). “Deregulated inflammasome signaling in disease”. Immunol Rev (Review). 243 (1): 163–73. doi:10.1111/j.1600-065X.2011.01042.x. PMC 3170132 . PMID 21884175.

  2. Some medical treatments can reduce the severity of the condition, but it can be difficult to cure.
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    A dermatologist can usually tell if someone has vitiligo just by looking for the telltale white patches. On people with fair skin, a special tool called a Woods lamp might be used. This lamp uses ultraviolet light in a dark room to illuminate areas of damaged skin that would otherwise be hard to see with the naked eye.
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    . Vitiligo—Part 2—classification, histopathology and treatment. An Bras Dermatol. 2014;89(5):784–790pmid:25184918
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    Requires a time commitment. Patients need 2 to 3 treatments per week for several weeks.
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  5. Thickening of the basement membrane
    . A pilot study assessing the role of 25 hydroxy vitamin D levels in patients with vitiligo vulgaris. J Am Acad Dermatol. 2010;62(6):937–941pmid:20466170

  6. Vascular, Lymphatic and Systemic Conditions
    Image credit: Grook Da Oger, (2011, July 22)
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    Although the causes of vitiligo aren’t completely understood, there are a number of different theories:
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    What are the symptoms of vitiligo?

  7. If white spots suddenly appear on your testicles, it may signal an underlying condition. Here’s what may be causing your symptoms and how to treat it.
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    The diagnosis of vitiligo is usually straightforward, and no special testing is needed. While vitiligo is a cutaneous problem and does not affect the health directly, it is disfiguring and may be psychologically traumatic. The condition cannot be cured at present, but treatments are available that may be very helpful. Medical treatments target the immune system, and try to reverse the destruction. Surgical treatments are less commonly done, and transplant healthy melanocytes from other areas. Both treatments may be difficult and prolonged.
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    Steroid creams are also commonly prescribed to help reduce or remove milia.
    Genetic Testing Registry: Vitiligo

  8. Schallreuter, K. U., Wood, J. M. & Berger, J. Low catalase levels in the epidermis of patients with vitiligo. J. Invest. Dermatol. 97, 1081–1085 (1991).
    Das, S. K., Majumder, P. P., Chakraborty, R., Majumdar, T. K. & Haldar, B. Studies on vitiligo. I. Epidemiological profile in Calcutta, India. Genet. Epidemiol. 2, 71–78 (1985).
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  9. Acrofacial vitiligo: fingers and periorificial areas[22]
    Lasers are also being used in the treatment of vitiligo, specifically the Excimer laser. They emit narrow band ultraviolet B light and have been shown to promote re-pigmentation. Treatment is undertaken in a series of laser sessions. Occasional touch-up booster sessions may be required.
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    Vitiligo can be categorized as one of three types, based on the pattern of depigmentation.
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  10. SPOT Skin Cancer™
    Vitiligo universalis is a widespread form of the disease that is generally seen in adults, although cases in children are reported.24 The term “universalis” refers to the almost virtually universal depigmentation (>60% to 90% of the body surface area) (Fig 2). Hairs may be partially spared. In general, vitiligo universalis is the result of generalized vitiligo that gradually progresses to nearly complete depigmentation of the skin.
    Vitiligo (vit-il-EYE-go) is a skin disorder that causes the skin to lose its color. Smooth lighter or white areas (called macules or patches) appear on a person’s skin. If vitiligo occurs in a hair-bearing area, the hair in those areas also may turn white.
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    These patches can appear anywhere on the body. Vitiligo is usually symmetric, though it can appear on only one side of the body. Typical areas affected by vitiligo include the knees, hands, genitals, and hair. It can also affect areas with mucous membranes, such as the inside of the mouth and nose.

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  12. Yang Y, Lin X, Fu W, Luo X, Kang K. An approach to the correlation between vitiligo and autoimmune thyroiditis in Chinese children. Clin Exp Dermatol. 2009 Oct 23. [Medline].
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    A dermatologist can usually tell if someone has vitiligo just by looking for the telltale white patches. On people with fair skin, a special tool called a Woods lamp might be used. This lamp uses ultraviolet light in a dark room to illuminate areas of damaged skin that would otherwise be hard to see with the naked eye.
    Vitiligo develops when cells called melanocytes (meh-lan-o-sites) die. These cells give our skin and hair color.
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    If symptoms are very minor, some people can prevent white patches from becoming obvious by not allowing their skin to tan.
    Mix Harad powder in garlic juice and apply it on the white spots.
    Drs. Taïeb and Picardo are coordinators of the VETF, whose meetings in Paris have been supported by Pierre Fabre Laboratories. Dr. Picardo serves as the president of the European Society for Pigment Cell Research, which received a donation from Galderma Laboratories to organize a workshop on vitiligo at the 2008 International Pigment Cell Conference. No other potential conflict of interest relevant to this article was reported.

  13. Resources
    Avoid citrus fruits, tamarind, fish, lobsters, crabs and prawns.
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    White skin spots are not usually a reason for concern and do not cause major symptoms.

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